A handling and actuation apparatus particularly adapted for clean room applications includes an actuation section for mounting a machine element to a work piece. The actuation section comprises a movable actuation member. A feeding section for feeding the aforementioned machine element to the actuation section is provided. An inner debris suction section is positioned in the vicinity of the actuation section, the inner debris suction section sucking air from the vicinity of the actuation member. An outer debris and air suction section is positioned in the vicinity of the feeding section sucks air from the vicinity of machine element during feeding of the machine element.