Patent 7238813 was granted and assigned to Smithkline Beecham Limited on July, 2007 by the United States Patent and Trademark Office.
Benzimidazole derivatives, which are useful as TIE-2 and/or VEGFR2 inhibitors are described herein. The described invention also includes methods of making such benzimidazole derivatives as well as methods of using the same in the treatment of hyperproliferative diseases.