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US Patent 7250438 Anti-bacterial and anti-cancer spiro beta-lactone/gamma-lactams

Patent 7250438 was granted and assigned to Nereus Pharmaceuticals on July, 2007 by the United States Patent and Trademark Office.

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Patent attributes

Current Assignee
‌
Nereus Pharmaceuticals
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
7250438
Patent Inventor Names
Barbara C. Potts0
Rama Rao Manam0
Date of Patent
July 31, 2007
Patent Application Number
11146613
Date Filed
June 6, 2005
Patent Primary Examiner
‌
Kamal A Saeed
Patent abstract

Disclosed herein are novel spiro beta-lactone/gamma lactams for use in treating bacterial infections and cancer. The compounds are characterized by a terminal electron-withdrawing group such as a nitro group. Screening data shows antimicrobial activity against various bacterial cell lines, particularly gram-positive bacteria, and anti-cancer activity.

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