A compact, portable tablet dispenser is particularly adapted for carrying aspirin tablets for ingestion as therapy upon the onset of a suspected heart attack. The tablets are in a blister within the dispenser, which includes actuators aligned with the tablets to eject the tablets through an aperture in the dispenser. Upon operation, the actuators provide a permanent indication that a tablet has been ejected. The dispenser may include electronic circuitry to provide reinforcement and/or guidance, for its use and may include means for alerting a third party, such as by a 911 call, of its activation.