Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Matthew B. Soellner0
Ronald T. Raines0
Date of Patent
August 14, 2007
Patent Application Number
10930702
Date Filed
August 30, 2004
Patent Primary Examiner
Patent abstract
The present invention is a method for a covalent ligation of one or more molecules to one or more surfaces, that is site-specific and both rapid and high yielding. The covalent ligation to the surface is based on the reaction of an azide and a phosphinothioester to form an amide bond. The method of the invention is particularly well-suited to the immobilization of peptides, proteins or protein fragments to surfaces.
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