Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Yukihiro Nishiyama0
Date of Patent
September 4, 2007
Patent Application Number
10477444
Date Filed
May 9, 2002
Patent Primary Examiner
Patent abstract
The present invention provides a herpes virus in which a non-essential gene for replication is inactivated More particularly, the present invention provides a herpes virus in which a non-essential gene for replication present in a UL or US region is inactivated. More preferably, the non-essential gene for replication contains US3 or UL56. The herpes virus may be preferably a herpes simplex virus, and more preferably herpes simplex virus 1 or herpes simplex virus 2. The present invention provides a method, composition and use for treating various diseases or disorders including tumor and infectious diseases. The present invention also provides a method, composition and use for activating a prodrug.
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