Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Bernd Groner0
Martin Göttlicher0
Peter Herrlich0
Thorsten Heinzel0
Date of Patent
September 4, 2007
0Patent Application Number
103323530
Date Filed
July 5, 2001
0Patent Primary Examiner
Patent abstract
The present invention relates to the use of the drug valproic acid and derivatives thereof as inhibitors of enzymes having histone deacetylase activity. The invention also relates to the use of those compounds for the manufacture of a medicament for the treatment of diseases which are associated with hypoacetylation of histones or in which induction of hyperacetylation has a beneficial effect for example by induction of differentiation and/or apoptosis in transformed cells.
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