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US Patent 7268229 Compounds to co-localize luminophores with luminescent proteins

Patent 7268229 was granted and assigned to Promega (company) on September, 2007 by the United States Patent and Trademark Office.

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Patent abstract

A method of measuring the enzymatic activity of a luciferase includes contacting a luminogenic protein, such as a luciferase, with a protected luminophore to form a composition; and detecting light produced from the composition. The protected luminophore provides increased stability and improved signal-to-background ratios relative to the corresponding unmodified coelenterazine.

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