Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Ethel Diane Williamson0
Julie Miller0
Leslie William James Baillie0
Date of Patent
September 18, 2007
0Patent Application Number
104831500
Date Filed
July 9, 2002
0Patent Primary Examiner
Patent abstract
A recombinant microorganism comprises an asporogenic Bacillus subtilis strain in which a gene encoding a protease enzyme has been downregulated or inactivated. In particular sigma factorspoIIAC is inactivated such that the strain is asporogenic. These strains are particularly useful as expression vehicles for proteins such as protective antigen (PA) of Bacillus anthracis.
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