Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Brian K. Shoichet0
Fabio Prati0
Date of Patent
September 18, 2007
Patent Application Number
10731738
Date Filed
December 9, 2003
Patent Citations Received
Patent Primary Examiner
Patent abstract
New carboxyphenyl-glycylboronic acid transition-state analog inhibitors, representative of a class of compounds effective against class C β-lactamase AmpC. The new compounds improve inhibition by over two-orders of magnitude compared to analogous glycylboronic acids, with Ki values as low as 1 nM.
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