Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Martin Fussenegger0
Wilfried Weber0
Date of Patent
September 25, 2007
0Patent Application Number
099494700
Date Filed
September 7, 2001
0Patent Primary Examiner
Patent abstract
The invention relates to a novel system for gene regulation in eukaryotic cells, and methods of using the same for protein production, tissue engineering and gene therapy. In particular, the invention provides a new system for antibiotic-regulated gene expression in eukaryotic cells based on sequences from Enterobacteriaceae antibiotic resistance promoters, polypeptides that bind to the same in an antibiotic responsive manner, and nucleotides encoding such polypeptides. Further, the invention provides novel and sensitive methods of screening for candidate antibiotics.
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