US Patent 7278968 Ultrasonograph

An ultrasonograph is provided wherein the decrease of the density of the stabilized microbubble contrast agent in a desired body target area can be inhibited, radiating ultrasonic energy required for satisfactory signal-to-noise ratio and sufficient frame rate, where an ultrasonic probe transmits an ultrasonic pulse acquired by superimposing higher harmonics including a second harmonic of the fundamental onto the fundamental wave, such as a maximum positive pressure enhanced waveform or a maximum negative pressure enhanced waveform, or an acoustic pressure rise enhanced waveform or an acoustic pressure fall enhanced waveform.