Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
October 9, 2007
Patent Application Number
11186448
Date Filed
July 21, 2005
Patent Primary Examiner
Patent abstract
Compositions and methods are provided for the treatment of conditions associated with cell proliferation, cell differentiation and cell survival. In particular, the dual-specificity phosphatase DSP-10, and polypeptide variants thereof that stimulate dephosphorylation of DSP-10 substrates, are provided. The polypeptides may be used, for example, to identify antibodies and other agents that inhibit DSP-10 activity. The polypeptides and agents may be used to modulate cell proliferation, differentiation, and survival.
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