A pipe thread protector includes a case, a first seal member, and a second seal member. The case is attachable to an end of a pipe to protect a threaded region of the pipe. The case has a cylindrical or frustoconical portion having threads over at least a portion of its length to engage the threaded region of the pipe, and an annular end portion configured to abut a distal end of the pipe. A first seal member is disposed at the cylindrical portion of the case, and a second seal member is disposed at the annular end portion of the case. At least one of the first and second seal members (i) is detachable from the case, and (ii) comprises a material different than a material of the case.