Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
October 23, 2007
Patent Application Number
10338462
Date Filed
January 8, 2003
Patent Primary Examiner
Patent abstract
Compositions and methods are provided for treating NF-κB-related conditions. In particular, the invention provides a stimulus-inducible IKK signalsome, and components and variants thereof. An IKK signalsome or component thereof may be used, for example, to identify antibodies and other modulating agents that inhibit or activate signal transduction via the NF-κB cascade. IKK signalsome, components thereof and/or modulating agents may also be used for the treatment of diseases associated with NF-κB activation.
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