Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
October 30, 2007
Patent Application Number
10366704
Date Filed
February 14, 2003
Patent Primary Examiner
Patent abstract
Cytotoxic tumor therapy in a patient is enhanced by co-administration of sphingomyelin. The invention most likely enhances a tumor cell's ability to undergo ceramide-induced apoptosis by increasing the levels of sphingomyelin in all cellular compartments, thereby providing sufficient substrate for activated sphingomyelinase. A method of treating rheumatoid arthritis also is provided.
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