Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
William S Kloetzer0
Nabil Hanna0
Date of Patent
November 13, 2007
0Patent Application Number
111437370
Date Filed
June 3, 2005
0Patent Primary Examiner
Patent abstract
The specification provides methods of preparing high-affinity antibodies to a macrophage migration inhibitory factor (MIF) in animals in which the MIF gene has been homozygously knocked-out (MIF−/−). Also provided are methods of preparing hybridomas which produce the anti-MIF antibodies, methods of administering the antibodies to treat inflammatory or cancerous conditions and/or diseases modulated by MIF, as well as compositions comprising said high-affinity anti-MIF antibodies.
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