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US Patent 7297494 Activatable probes and methods for in vivo gene detection

Patent 7297494 was granted and assigned to Georgia Tech Research Corporation on November, 2007 by the United States Patent and Trademark Office.

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Patent abstract

Probes for detecting a target polynucleotide are provided. One aspect provides a molecular beacon probe set wherein the donor molecular beacon comprises a quantum dot and an acceptor molecular beacon comprises at least one reporter. The probes optionally comprise a protein transduction domain, targeting signal, or a combination thereof. Methods for detecting target polynucleotides using the disclosed probes are also provided.

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