Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
November 20, 2007
Patent Application Number
10627882
Date Filed
July 25, 2003
Patent Primary Examiner
Patent abstract
Large circular (LC)-sense molecules in an array is disclosed. The LC-sense molecules array is combined with cDNA hybridization to detect differences in expression profile between different cells. LC-sense molecules were purified from nonredundant clones with recombinant phagemid and arrayed onto silanized slide glasses. By hybridization of LC-sense array with Cy3 or Cy5-labelled cDNA preparations at 60° C., 29 up-regulated and 6 down-regulated genes in cancerous liver tissue were detected.
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