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Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Benjamin T. Dorner0
Lushi Tan0
Nobuyoshi Yasuda0
Wenjie Li0
Frederick W. Hartner0
Date of Patent
November 27, 2007
0Patent Application Number
114101790
Date Filed
April 24, 2006
0Patent Primary Examiner
Patent abstract
The present invention relates to synthetic processes useful in the preparation of fluorinated 4-azasteroid derivatives that modulate androgen receptors and have application in the treatment of conditions caused by androgen deficiency or androgen receptor hyperactivity, such as osteoporosis, periodontal disease, bone fracture, frailty, erectile dysfunction, loss of libido, androgen-dependent cancers and sarcopenia. The present invention also encompasses intermediates useful in the disclosed synthetic processes and the methods of their preparation.
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