Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
George Inana0
Margaret McLaren0
Date of Patent
December 18, 2007
0Patent Application Number
107734460
Date Filed
February 9, 2004
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The invention discloses multiple genes related to age-related macular degeneration (AMD) and/or phagocytosis by RPE cells of the eye, and methods and compositions for detecting and treating AMD and other retinal degenerative conditions based on these phagocytosis-related and/or AMD-related genes. Also provided are animal models useful for testing therapeutic compounds and treatment protocols for AMD, and gene arrays including polymorphic variants of phagocytosis-related and/or AMD-related genes, useful for genetic screening of nucleic acid samples from subjects to obtain profiles of polymorphic variant sequences in a plurality of genes associated with AMD.
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