Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Katsuo Sueishi0
Yasuhiro Ikeda0
Yoshikazu Yonemitsu0
Yoshiyuki Inada0
Kensuke Egashira0
Date of Patent
December 18, 2007
0Patent Application Number
102769710
Date Filed
May 25, 2001
0Patent Primary Examiner
Patent abstract
The present invention provides a prophylactic and/or therapeutic agent for pulmonary hypertension, comprising an antagonistic mutein of MCP-1 or a salt thereof, a DNA molecule comprising a nucleotide sequence encoding the antagonistic mutein of MCP-1, or a neutralizing antibody against MCP-1. The antagonistic mutein of MCP-1 or a salt thereof, the DNA molecule having a nucleotide sequence encoding the antagonistic mutein of MCP-1, or the neutralizing antibody against MCP-1 has hypotensive activity, and thus is useful as a pharmaceutical agent for preventing and/or treating pulmonary hypertension (primary pulmonary hypertension, in particular).
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