Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Chi Shung Brian To0
Aaron R Goerke0
Ann L. Lee0
John O. Konz, Jr.0
Date of Patent
February 5, 2008
0Patent Application Number
105127790
Date Filed
May 13, 2003
0Patent Citations Received
0
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Patent Primary Examiner
Patent abstract
A process for purifying virus particles, especially recombinant adenovirus vector particles, is presented. The process relies on various combinations of cell lysis, detergent-based precipitation of host cell contaminants away from the virus, depth filtration or centrifugation, ultrafiltration, nuclease digestion and chromatography to robustly and economically produce highly purified product. This process results in contaminating DNA levels which are consistently below detectable levels.
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