Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Donald Robert Dunbar0
John Anthony Morrow0
Deborah Grace Tolan0
Date of Patent
February 12, 2008
0Patent Application Number
102962700
Date Filed
May 22, 2001
0Patent Primary Examiner
Patent abstract
This invention relates to a DNA sequence encoding a member of the hyperpolarized activated ion channel family (HCN) and variants thereof, and the use of said sequences in assays for the measurement of gene expression. It also relates to assays for screening of Ih activators and blockers for clinical and therapeutic use in the management of human psychiatric and neurological dysfunction in the CNS, cardiovascular dysfunction of the heart, and reproductive dysfunction and/or contraception related to Ih function in testes and spermatozoa. Further, antibodies against the expressed DNA sequences and other compounds reactive with the expressed DNA sequence are also part of the invention.
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