Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Roeland Nusse0
Karl H. Willert0
Date of Patent
February 26, 2008
0Patent Application Number
115953570
Date Filed
November 9, 2006
0Patent Primary Examiner
Patent abstract
Compositions of purified biologically active Wnt proteins are provided. Wnt proteins are found to be hydrophobic and post-translationally modified by addition of a lipid moiety at a conserved cysteine residue. Methods for isolation of Wnt utilize detergents that maintain the solubility of the modified protein.
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