Patent 7335653 was granted and assigned to ChemoCentryx on February, 2008 by the United States Patent and Trademark Office.
Compounds are provided that act as potent antagonists of chemokine receptors. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of chemokine receptor-mediated diseases, and as controls in assays for the identification of chemokine antagonists.