Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
March 4, 2008
Patent Application Number
11063308
Date Filed
February 22, 2005
Patent Primary Examiner
Patent abstract
A novel sarR gene and sarR gene product which down regulates the expression of sarA and the resulting virulence determinants in Staphylococcus aureus is provided. Methods for modulating the expression of sarA and virulence determinants are also provided. A preferred embodiment of the present invention provides structural information relating to the gene product and enables the identification and formulation of lead compounds and reducements for treating and preventing infections by S. aureus and related bacteria.
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