Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Hiroo Matsumoto0
Syuji Morikiyo0
Yasutaka Takada0
Yuji Yoshimura0
Masami Yasukawa0
Michiaki Adachi0
Date of Patent
March 4, 2008
0Patent Application Number
105281790
Date Filed
September 11, 2003
0Patent Primary Examiner
Patent abstract
A method for producing an alkyl (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxy-6-heptenoate of the formula (1) (wherein R is a C1-4 alkyl group), which is an intermediate for a cholesterol-reducing agent (a HMG-CoA reductase inhibitor), etc. A solution containing a compound of the formula (1) is subjected to liquid chromatography treatment using silica gel as the packing material, to separate its epimers contained therein.
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