Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
David R. Harder0
James B. Antczak0
Lane Brostrom0
Date of Patent
March 11, 2008
0Patent Application Number
114148960
Date Filed
May 1, 2006
0Patent Primary Examiner
Patent abstract
Methods and uses are described for treating or preventing diseases of humans or non-human animals by reducing the amount of active leukotriene B4 (LTB4) in those in need of such treatment using LTB4 hydroxylases. In certain embodiments, LTB4 hydroxylase is administered in combination with nicotinamide adenine dinucleotide phosphate and/or an NADPH-cytochrome P-450 reductase. The invention is particularly useful for treating or preventing respiratory diseases that are caused or exacerbated by inflammation.
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