Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Jere W. McBride0
Xue-Jie Yu0
David H. Walker0
Date of Patent
March 18, 2008
Patent Application Number
10731554
Date Filed
December 9, 2003
Patent Primary Examiner
Patent abstract
The present invention is directed to the cloning, sequencing and expression of homologous immunoreactive 28-kDa protein genes, p28-1, -2, -3, -5, -6, -7, -9, from a polymorphic multiple gene family of Ehrlichia canis. Further disclosed is a multigene locus encoding all nine homologous 28-kDa protein genes of Ehrlichia canis. Recombinant Ehrlichia canis 28-kDa proteins react with convalescent phase antiserum from an E. canis-infected dog, and may be useful in the development of vaccines and serodiagnostics that are particularly effective for disease prevention and serodiagnosis.
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