Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Massimo Maffei0
Mario Contorni0
Date of Patent
March 25, 2008
0Patent Application Number
104847020
Date Filed
July 26, 2002
0Patent Citations Received
Patent Primary Examiner
Patent abstract
To improve the stability of vaccines comprising aluminum salt(s), the invention uses the amino acid histidine. This can improve pH stability and adjuvant adsorption and can be reduce antigen hydrolysis. Histidine is preferably presen during adsorption to the aluminium salt(s). The antigen in the vaccine may be a protein or a saccharide and is preferably from N. meningitidis.
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