Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Isa Gokce0
Jeremy Hugh Lakey0
Gregor Anderluh0
Date of Patent
March 25, 2008
0Patent Application Number
105010710
Date Filed
January 10, 2003
0Patent Primary Examiner
Patent abstract
The present invention relates to fusion proteins (fusion polypeptides), particularly for use in expression and/or purification systems. The present inventors have found that the TolAIII domain has remarkable properties which are of particular use as a fusion protein partner to achieve high levels of expression in a host cell. In one aspect of the invention, a TolAIII domain or a functional homologue, fragment, or derivative thereof is located towards the N-terminus of the fusion polypeptide and a non-TolA polypeptide is located towards the C-terminus of the fusion polypeptide.
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