Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Christoph Lengauer0
Bert Vogelstein0
Kenneth W. Kinzler0
Prasad Jallepalli0
Date of Patent
April 8, 2008
0Patent Application Number
098153400
Date Filed
March 23, 2001
0Patent Primary Examiner
Patent abstract
Securin-deficient cells and their isogenic securin-proficient counterparts are useful for screening potential anti-tumor agents. Potential therapeutic agents are screened for the ability to preferentially inhibit or kill a securin-deficient cell. The association of securin deficiency and chromosomal instability leading to aneuploidy, renders securin an excellent target for chemotherapeutic drug development.
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