Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Edward Sellers0
Rachel Tyndale0
Date of Patent
May 13, 2008
0Patent Application Number
116825050
Date Filed
March 6, 2007
0Patent Primary Examiner
Patent abstract
A method of regulating the activity of human cytochrome P450 isozyme CYP2A6 to control nicotine metabolism or decrease to production of carcinogens from procarcinogens, such as those present in tobacco smoke, in an individual by selectively inhibiting CYP2A6. Various prophylactic (i.e., prevention and treatment) compositions and methods are also described, including an improved oral nicotine composition and method comprising the use of nicotine together with an inhibitor of the CYP2A6 enzyme.
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