Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
John Bryan Jones0
Richard R. Bott0
Benjamin G. Davis0
Date of Patent
May 13, 2008
0Patent Application Number
109938270
Date Filed
November 19, 2004
0Patent Primary Examiner
Patent abstract
This invention provides modified enzymes comprising one or more amino acid residues replaced by cysteine residues, where the cysteine residues are modified by replacing the thiol hydrogen in the cysteine residues with a substituent group providing a thiol side chain comprising a multiply charged moiety. The enzymes show improved interaction and/or specificity and/or activity with charged substrates.
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