Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Date of Patent
May 13, 2008
Patent Application Number
11045947
Date Filed
January 29, 2005
Patent Primary Examiner
Patent abstract
This invention relates to methods of inducing dephosphorylation of a hyperphosphorylated cell cycle regulatory protein in a tumor cell in which hyperphosphorylation of said protein contributed to cell transformation, the method comprising contacting the tumor cell with a procyanidin oligomer of five monomeric units connected via a C-4→C-8 linkage. Examples of such compounds are [EC-(4β→8)]4-EC, and [EC-(4β→8)]3-EC-(4β→8)-C, wherein EC is epicatcchin and C is catechin.
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