Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Anke Tschentscher0
Antje Gupta0
Maria Bobkova0
Date of Patent
May 13, 2008
0Patent Application Number
115689050
Date Filed
April 29, 2005
0Patent Primary Examiner
Patent abstract
The invention relates to a process for the preparation of 2-butanol by enzymatic-catalyzed reduction of 2-butanone with a carbonyl reductase and a coenzyme and is characterized in that an aqueous phase, which contains the carbonyl reductase and the coenzyme, is contacted with an alcoholic phase, which is not miscible with the aqueous phase and contains 2-butanone, in order to reduce the 2-butanone, with the proviso that the alcohol present in the alcoholic phase is a secondary alcohol capable of regenerating the coenzyme and exhibiting a boiling point which lies above that of water, whereupon the 2-butanol formed is separated.
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