US Patent 7375228 Histone deacetylase inhibitors

Patent 7375228 was granted and assigned to Takeda (company) on May, 2008 by the United States Patent and Trademark Office.

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Patent Citations Received

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US Patent 11919839 Alpha-cinnamide compounds and compositions as HDAC8 inhibitors

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Patent Inventor Names

Andrew J. Jennings0

Anthony R. Gangloff0

Jason W. Brown0

Jeffrey A. Stafford0

Jerome C. Bressi0

Phong H. Vu0

Sheldon X. Cao0

Xiao-Yi Xiao0

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Patent abstract

Compounds that may be used to inhibit histone deacetylase having the formulaZ-Q-L-M or Z-L-Mwherein M is a substituent capable of complexing with a deacetylase catalytic site and/or a metal ion; L is a substituent providing between 0-10 atoms separation between the M substituent and the remainder of the compound; and Z and Q are as defined herein.

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