US Patent 7378516 Synthesis of sulfurized oligonucleotides
Patent 7378516 was granted and assigned to Ionis Pharmaceuticals on May, 2008 by the United States Patent and Trademark Office.
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Patent abstract
Methods for the formation of sulfurized oligonucleotides are provided. The methods allow for the formation of phosphorothioate linkages in the oligonucleotides or derivatives, without the need for complex solvent mixtures and repeated washing or solvent changes. Oligonucleotides having from about 8, and up to about 50, nucleotides can be sulfurized according to the methods of the invention with higher yields than have been previously reported.
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US Patent 07378516 Synthesis of sulfurized oligonucleotides US Patent 7378516 Synthesis of sulfurized oligonucleotides
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Patent Number
0737851600
Patent Number
737851600
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Infobox
Is a
Current Assignee
Patent Jurisdiction
Patent Number
073785160
Date of Patent
May 27, 2008
0Patent Application Number
108475020
Date Filed
May 17, 2004
0Official Website
Patent Primary Examiner
Edits on 28 Sep, 2022
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Infobox
Is a
Current Assignee
Patent Jurisdiction
Patent Number
073785160
Date of Patent
May 27, 2008
0Patent Application Number
108475020
Date Filed
May 17, 2004
0Official Website
Patent Primary Examiner
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US Patent 07378516 Synthesis of sulfurized oligonucleotides
Infobox
Is a
Current assignee
Patent jurisdiction
Patent number
07378516
Date of patent
May 27, 2008
Patent application number
10847502
Date Filed
May 17, 2004
Patent primary examiner
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