Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Jamal El Yazal0
Shannon A Marshall0
Rene S. Hubert0
John R. Desjarlais0
Date of Patent
June 3, 2008
0Patent Application Number
106113630
Date Filed
July 1, 2003
0Patent Primary Examiner
Patent abstract
The present invention relates to novel, soluble, recombinant RANKL (Receptor Activator of Nuclear Factor—κB Ligand) variant proteins which may be expressed solubly in E. coli, variants that have substantially reduced binding to OPG, variants that act as RANKL antagonists, and methods for generating the same.
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