Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Edward Rockenstein0
Margaret E. Mallory0
Eliezer Masliah0
Date of Patent
July 1, 2008
0Patent Application Number
099336400
Date Filed
August 20, 2001
0Patent Citations Received
Patent Primary Examiner
Patent abstract
Alzheimer's disease, Parkinson's disease and Lewy body disease are the most commonly found neurodegenerative disorders in the elderly. The invention is a transgenic mouse that contains two transgenes, human α-synuclein and human amyloid precursor protein, which are responsible for the formation of the neuritic plaques, Lewy bodies and neurodegeneration seen in the above mentioned diseases. The transgenic mouse is an accurate model for disease by both functional and pathological assays.
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