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US Patent 7399781 N-substituted benzothiophenesulfonamide derivatives

Patent 7399781 was granted and assigned to TOA EIYO on July, 2008 by the United States Patent and Trademark Office.

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Patent abstract

The present invention relates to an N-substituted benzothiophenesulfonamide derivative or a pharmaceutically acceptable salt thereof and applications thereof. Furthermore, it provides an agent for preventing or treating cardiac or circulatory disease and so on caused by abnormal increase of production of angiotensin II or endothelin I based on chymase activity, or by activation of mast cell, and an agent for preventing adhesion after surgery, wherein the agent has a selective inhibitory action on chymase.

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