Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Vincent Dubois0
Alexandre Passioukov0
André Trouet0
Date of Patent
July 22, 2008
Patent Application Number
10362958
Date Filed
August 23, 2001
Patent Citations Received
Patent Primary Examiner
Patent abstract
The product of the invention is a modified form of a therapeutic agent and comprises a therapeutic agent, an oligopeptide having a plasmin peptide substrate of 2-4 amino acids and mono- or di-peptide linkage, a stabilizing group and, optionally, a linker group. The prodrug is cleavable by plasmin. Also disclosed are methods of making and using the prodrug compounds.
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