US Patent 7404278 Method for producing prefillable syringes

A method for producing prefillable syringes includes the steps of producing syringe bodies with a cylindrical drum portion which has a first open end for receiving a syringe plunger and has a second open end for discharging of contents. An inner surface of each syringe body is then cleaned. Siliconization is then performed by applying a quantity of silicone oil or silicone emulsion to at least a partial area of the inner surface of each syringe body. Some of the applied quantity of silicone is then removed. Finally, the syringe bodies are packaged. The siliconization, removing and packaging steps are all carried out under controlled clean-room conditions.