US Patent 7405284 Reducing cellular dysfunction caused by mitochondrial gene mutations
Patent 7405284 was granted and assigned to University of Florida on July, 2008 by the United States Patent and Trademark Office.
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Patent Inventor Names
John Guy0
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Patent abstract
A synthetic, nuclear-encoded ND4 gene was linked to a mitochondrial targeting sequence and a FLAG epitope tag. This fusion construct was inserted into a rAAV vector. The ND4 fusion protein was expressed and imported into the mitochondria of cells harboring a mitochondrial DNA mutation (G11778A), where it restored cellular respiration.
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US Patent 07405284 Reducing cellular dysfunction caused by mitochondrial gene mutations US Patent 7405284 Reducing cellular dysfunction caused by mitochondrial gene mutations
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Patent Number
074052840
Patent Number
74052840
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Current Assignee
Patent Jurisdiction
Patent Number
074052840
Date of Patent
July 29, 2008
0Patent Application Number
106876770
Date Filed
October 17, 2003
0Official Website
Patent Primary Examiner
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US Patent 07405284 Reducing cellular dysfunction caused by mitochondrial gene mutations
Infobox
Is a
Current assignee
Patent jurisdiction
Patent number
07405284
Date of patent
July 29, 2008
Patent application number
10687677
Date Filed
October 17, 2003
Patent primary examiner
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