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US Patent 7407630 High density plate filler

Patent 7407630 was granted and assigned to Applera on August, 2008 by the United States Patent and Trademark Office.

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Patent
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Patent attributes

Current Assignee
‌
Applera
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
7407630
Date of Patent
August 5, 2008
Patent Application Number
11086271
Date Filed
March 22, 2005
Patent Citations Received
‌
US Patent 11977087 Systems, devices, and methods for ultra-sensitive detection of molecules or particles
0
‌
US Patent 11686208 Abrasive coating for high-temperature mechanical systems
0
Patent Primary Examiner
Alfred Worden
Alfred Worden
Patent abstract

A filling apparatus for filling a microplate. The microplate having a plurality of wells each sized to receive an assay. The filling apparatus can comprise an assay input layer having a first surface and an opposing second surface. The assay input layer can comprise an assay input port extending from the first surface to the second surface, a venting manifold formed in the second surface, and a vent hole in fluid communication with the venting manifold and atmosphere. An output layer can comprise a plurality of staging capillaries each having an inlet and an outlet. A venting layer can be disposed between the assay input layer and the output layer. The venting layer can comprise a plurality of microfluidic channels, a flow aperture being in fluid communication with the assay input port and the plurality of microfluidic channels, and a plurality of vent apertures each in fluid communication with at least one of the plurality of staging capillaries. Two or more of the plurality of vent apertures can be in fluid communication with the venting manifold.

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