Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
August 5, 2008
Patent Application Number
11598375
Date Filed
November 13, 2006
Patent Primary Examiner
Patent abstract
The invention provides methods for producing products comprising improved host cells genetically engineered to have uncoupled productive and catabolic pathways. In particular, the present invention provides host cells having a modification in nucleic acid encoding an endogenous enzymatic activity that phosphorylates D-glucose at its 6th carbon and/or a modification of nucleic acid encoding an enzymatic activity that phosphorylates D-gluconate at its 6th carbon. Such improved host cells are used for the production of products, such as, ascorbic acid intermediates. Methods for making and using the improved host cells are provided. Nucleic acid and amino acid sequences for glucokinase and gluconokinase are provided.
Timeline
No Timeline data yet.
Further Resources
No Further Resources data yet.
