Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Lynda S. Ostedgaard0
John A. Chiorini0
Mark F. Stinski0
Michael J. Welsh0
Date of Patent
August 5, 2008
0Patent Application Number
110054100
Date Filed
December 6, 2004
0Patent Citations Received
0
Patent Primary Examiner
Patent abstract
The present invention relates to nucleic acid molecules comprising certain truncated forms of the human cytomegalovirus (CMV) immediate-early enhancer-promoter, either alone or operably linked to transgenes of interest, including those encoding partially-deleted CFTR proteins. This invention further relates to vectors comprising these nucleic acid molecules and host cells transformed by such vectors. The nucleic acid molecules, vectors and transformed host cells of the present invention are useful for treating a variety of genetic, metabolic and acquired diseases, including inter alia cystic fibrosis (CF) airway disease.
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