US Patent 7413536 Substrates and screening methods for transport proteins

Patent 7413536 was granted and assigned to Xenoport, Inc. on August, 2008 by the United States Patent and Trademark Office.

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Patent Inventor Names

Kenneth C. Cundy1

Mark A. Gallop1

Ronald W. Barrett1

Tania Chernov-Rogan1

William J. Dower1

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Patent abstract

A variety of methods for assaying libraries of test compounds as ligands and/or substrates of transport proteins, including both carrier-type and receptor-type transport proteins, are provided. Both in vitro and in vivo screening methods are disclosed. Also provided are methods for screening DNA libraries to identify members that encode transport proteins. Pharmaceutical compositions including compounds identified via the screening methods are also provided.

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Official Website

https://pdfpiw.uspto.gov/.piw?Docid=074135361

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