Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Robert A. Olmsted0
Sergey Dryga0
Elizabeth A. Reap0
Jeffrey D. Chulay0
John S. Morris0
Date of Patent
September 2, 2008
0Patent Application Number
108867730
Date Filed
July 8, 2004
0Patent Citations Received
Patent Primary Examiner
Patent abstract
The present invention provides methods and compositions comprising a population of alphavirus replicon particles comprising alphavirus replicon RNAs, wherein a first replicon RNA comprises nucleic acid encoding cytomegalovirus pp65 and IE1 protein or immunogenic fragments thereof, and a second replicon RNA comprises nucleic acid encoding cytomegalovirus gB protein or an immunogenic fragment thereof, and wherein each of the two replicon RNAs is contained within a separate alphavirus replicon particle.
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